Anion...π, lone pair...π, and F...F interactions in nucleobase derivatives

The role of nucleobase interactions in RNA structure and dynamics

The intricate network of interactions observed in RNA three-dimensional structures is often described in terms of a multitude of geometrical properties, including helical parameters, base pairing/stacking, hydrogen bonding and backbone conformation. We show that a simple molecular representation consisting in one oriented bead per nucleotide can account for the fundamental structural properties...

Syntheses of 15N-labeled pre-queuosine nucleobase derivatives

Pre-queuosine or queuine (preQ1) is a guanine derivative that is involved in the biosynthetic pathway of the hypermodified tRNA nucleoside queuosine (Que). The core structure of preQ1 is represented by 7-(aminomethyl)-7-deazaguanine (preQ1 base). Here, we report the synthesis of three preQ1 base derivatives with complementary (15)N-labeling patterns, utilizing [(15)N]-KCN, [(15)N]-phthalimide, ...

lone pair - and cation - interactions coexist ? A theoretical study

© Versita Sp. z o.o. Received 30 July 2010; Accepted 28 September 2010

Liquid-crystalline supramolecular polymers formed through complementary nucleobase-pair interactions.

We report how the placement of nucleobase units, thymine, or N6-(4-methoxybenzoyl)adenine, onto the ends of a mesogenic core, bis-4-alkoxy-substituted bis(phenylethynyl)benzene, affects the properties of these materials. We show that addition of these bulky polar groups significantly reduces the range of liquid-crystalline behavior of these compounds. However, mixing two complementary nucleobas...

Nucleobase-fluorobenzene interactions: hydrogen bonding wins over pi stacking.